All journal publications (1963-2013)

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2012
Wennekes, T., Bonger, K.M., Vogel, K., van den Berg, R.J.B.H.N., Strijland, A., Donker-Koopman, W.E., Aerts, J.M.F.G., van der Marel, G.A., Overkleeft, H.S. , The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction, European Journal of Organic Chemistry, no. 32, pp. 6420-6454.
Kallemeijn, W.W., Li, K.Y., Witte, M.D., Marques, A.R.A., Aten, J., Scheij, S., Jiang, J.B., Willems, L. I, Voorn-Brouwer, T.M., van Roomen, C.P.A.A., Ottenhoff, R., Boot, R.G., van den Elst, H., Walvoort, M.T.C., Florea, B. I, Codee, J.D.C., van der Marel, G.A., Aerts, J.M.F.G., Overkleeft, H.S. , Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining beta-Exoglucosidases In Situ and In Vivo, Angewandte Chemie-International Edition, vol. 51, no. 50, pp. 12529-12533.
Walvoort, M.T.C., Kallemeijn, W.W., Willems, L. I, Witte, M.D., Aerts, J.M.F.G., van der Marel, G.A., Codee, J.D.C., Overkleeft, H.S. , Tuning the leaving group in 2-deoxy-2-fluoroglucoside results in improved activity-based retaining beta-glucosidase probes, Chemical Communications, vol. 48, no. 84, pp. 10386-10388.
2011
Willems, L. I, Van der Linden, W.A., Li, N., Li, K.Y., Liu, N., Hoogendoorn, S., Van der Marel, G.A., Florea, B. I, Overkleeft, H.S. , Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling, Accounts of Chemical Research, vol. 44, no. 9, pp. 718-729.
Clerc, J., Li, N., Krahn, D., Groll, M., Bachmann, A.S., Florea, B. I, Overkleeft, H.S., Kaiser, M. , The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity, Chem Commun (Camb), vol. 47, no. 1, pp. 385-7. DOI
2010
Geurink, P.P., Liu, N., Spaans, M.P., Downey, S.L., van den Nieuwendijk, A., van der Marel, G.A., Kisselev, A.F., Florea, B. I, Overkleeft, H.S. , Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome's Chymotrypsin-like Sites, Journal of Medicinal Chemistry, vol. 53, no. 5, pp. 2319-2323. DOI
Wennekes, T., van den Berg, R., Boltje, T.J., Donker-Koopman, W.E., Kuijper, B., van der Marel, G.A., Strijland, A., Verhagen, C.P., Aerts, J., Overkleeft, H.S. , Synthesis and Evaluation of Lipophilic Aza-C-glycosides as Inhibitors of Glucosylceramide Metabolism, European Journal of Organic Chemistry, no. 7, pp. 1258-1283. DOI
van Scherpenzeel, M., van den Berg, R., Donker-Koopman, W.E., Liskamp, R.M.J., Aerts, J., Overkleeft, H.S., Pieters, R.J. , Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase, Bioorganic & Medicinal Chemistry, vol. 18, no. 1, pp. 267-273. DOI
2009
Witte, M.D., Florea, B. I, Verdoes, M., Adeyanju, O., Van der Marel, G.A., Overkleeft, H.S. , O-GlcNAc Peptide Epoxyketones Are Recognized by Mammalian Proteasomes, Journal of the American Chemical Society, vol. 131, no. 34, pp. 12064-+. DOI
Clerc, J., Florea, B. I, Kraus, M., Groll, M., Huber, R., Bachmann, A.S., Dudler, R., Driessen, C., Overkleeft, H.S., Kaiser, M. , Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild-Type and Bortezomib-Adapted Leukaemic Cell Lines, Chembiochem, vol. 10, no. 16, pp. 2638-2643. DOI
Ruckrich, T., Kraus, M., Gogel, J., Beck, A., Ovaa, H., Verdoes, M., Overkleeft, H.S., Kalbacher, H., Driessen, C. , Characterization of the ubiquitin-proteasome system in bortezomib-adapted cells, Leukemia, vol. 23, no. 6, pp. 1098-1105. DOI
Verdoes, M., Florea, B. I, van der Marel, G.A., Overkleeft, H.S. , Chemical Tools To Study the Proteasome, European Journal of Organic Chemistry, no. 20, pp. 3301-3313. DOI
Klein, T., Geurink, P.P., Overkleeft, H.S., Kauffman, H.K., Bischoff, R. , Functional Proteomics on Zinc-Dependent Metalloproteinases using Inhibitor Probes, Chemmedchem, vol. 4, no. 2, pp. 164-170. DOI
Risseeuw, M.D.P., van den Berg, R., Donker-Koopman, W.E., van der Marel, G.A., Aerts, J., Overhand, M., Overkleeft, H.S. , Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors, Bioorganic & Medicinal Chemistry Letters, vol. 19, no. 23, pp. 6600-6603. DOI
Geurink, P., Klein, T., Leeuwenburgh, M., van der Marel, G., Kauffman, H., Bischoff, R., Overkleeft, H. , A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol, Org Biomol Chem, vol. 6, no. 7, pp. 1244-50. DOI
Wennekes, T., van den Berg, R., Boot, R.G., van der Marel, G.A., Overkleeft, H.S., Aerts, J. , Glycosphingolipids-Nature, Function, and Pharmacological Modulation, Angewandte Chemie-International Edition, vol. 48, no. 47, pp. 8848-8869. DOI
2008
Kuijl, C., Tuin, A.W., Overkleeft, H., Neefjes, J. , Reciprocal chemical genetics for swift lead and target identification, Molecular Biosystems, vol. 4, no. 10, pp. 1001-1008. DOI
Verdoes, M., Florea, B. I, Hillaert, W., Willems, L. I, van der Linden, W.A., Sae-Heng, M., Filippov, D.V., Kisseley, A.F., van der Marel, G.A., Overkleeft, H.S. , Azido-BODIPY acid reveals quantitative Staudinger-Bertozzi ligation in two-step activity-based proteasome profiling, Chembiochem, vol. 9, no. 11, pp. 1735-1738. DOI
Kraus, M., Malenke, E., Gogel, J., Muller, H., Ruckrich, T., Overkleeft, H., Ovaa, H., Koscielniak, E., Hartmann, J.T., Driessen, C. , Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis, Molecular Cancer Therapeutics, vol. 7, no. 7, pp. 1940-1948. DOI
Geurink, P., Klein, T., Leeuwenburgh, M., van der Marel, G., Kauffman, H., Bischoff, R., Overkleeft, H. , A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol, Organic & Biomolecular Chemistry, vol. 6, no. 7, pp. 1244-1250. DOI
2007
Risseeuw, M.D.P., Overhand, M., Fleet, G.W.J., Simone, M. I , A compendium of sugar amino acids (SAA): scaffolds, peptide- and glyco-mimetics, Tetrahedron-Asymmetry, vol. 18, no. 17, pp. 2001-2010. DOI
van Swieten, P.F., Samuel, E., Hernandez, R.O., van den Nieuwendijk, A.M.C.H., Leeuwenburgh, M.A., van der Marel, G.A., Kessler, B.M., Overkleeft, H.S., Kisselev, A.F. , A cell-permeable inhilbitor and activity-based probe for the caspase-like activity of the proteasome, Bioorganic & Medicinal Chemistry Letters, vol. 17, no. 12, pp. 3402-3405. DOI
Rohrig, C.H., Loch, C., Guan, J.Y., Siegal, G., Overhand, M. , Fragment-based synthesis and SAR of modified FKBP ligands: Influence of different linking on binding affinity, Chemmedchem, vol. 2, no. 7, pp. 1054-1070. DOI
Kraus, M., Ruckrich, T., Reich, M., Gogel, J., Beck, A., Kammer, W., Berkers, C.R., Burg, D., Overkleeft, H., Ovaa, H., Driessen, C. , Activity patterns of proteasome subunits reflect bortezomib sensitivity of hematologic malignancies and are variable in primary human leukemia cells, Leukemia, vol. 21, no. 1, pp. 84-92.
Risseeuw, M.D.P., Mazurek, J., van Langenvelde, A., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Synthesis of alkylated sugar amino acids: conformationally restricted L-Xaa-L-Ser/Thr mimics, Organic & Biomolecular Chemistry, vol. 5, no. 14, pp. 2311-2314. DOI
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