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Khan, S., Weterings, J.J., Britten, C.M., de Jong, A.R., Graafland, D., Melief, C.J.M., van der Burg, S.H., van der Marel, G., Overkleeft, H.S., Filippov, D.V., Ossendorp, F. , Chirality of TLR-2 ligand Pam(3)CysSK(4) in fully synthetic peptide conjugates critically influences the induction of specific CD8(+) T-cells, Molecular Immunology, vol. 46, no. 6, pp. 1084-1091. DOI
Burster, T., Beck, A., Poeschel, S., Oren, A., Baechle, D., Reich, M., Roetzschke, O., Falk, K., Boehm, B.O., Youssef, S., Kalbacher, H., Overkleeft, H., Tolosa, E., Driessen, C. , Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro, Immunology, vol. 121, no. 1, pp. 82-93. DOI
Weterings, J.J., Khan, S., van der Heden, G.J., Drijfhout, J.W., Melief, C.J.M., Overkleeft, H.S., van der Burg, O.H., Ossendorp, F., van der Marel, G.A., Filippov, D.V. , Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: Towards synthetic epitope-based vaccines, Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 12, pp. 3258-3261.
Lautwein, A., Kraus, M., Reich, M., Burster, T., Brandenburg, J., Overkleeft, H.S., Schwarz, G., Kammer, W., Weber, E., Kalbacher, H., Nordheim, A., Driessen, C. , Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner, Journal of Leukocyte Biology, vol. 75, no. 5, pp. 844-855.
Welters, M.J.P., Filippov, D.V., van den Eeden, S.J.F., Franken, K.L.M.C., Nouta, J., Valentijn, A.R.P.M., van der Marel, G.A., Overkleeft, H.S., Lipford, G., Offringa, R., Melief, C.J.M., van Boom, J.H., van der Burg, S.H., Drijfhout, J. , Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model, Vaccine, vol. 23, no. 3, pp. 305-311.
Wiendl, H., Lautwein, A., Mitsdorffer, M., Krause, S., Erfurth, S., Wienhold, W., Morgalla, M., Weber, E., Overkleeft, H.S., Lochmuller, H., Melms, A., Tolosa, E., Driessen, C. , Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies, Journal of Neuroimmunology, vol. 138, no. 1-2, pp. 132-143.
Kessler, B., Hong, X., Petrovic, J., Borodovsky, A., Dantuma, N.P., Bogyo, M., Overkleeft, H.S., Ploegh, H., Glas, R. , Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production, Journal of Biological Chemistry, vol. 278, no. 12, pp. 10013-10021.
Greiner, A., Lautwein, A., Overkleeft, H.S., Weber, E., Driessen, C. , Activity and subcellular distribution of cathepsins in primary human monocytes, Journal of Leukocyte Biology, vol. 73, no. 2, pp. 235-242.
Lautwein, A., Burster, T., Lennon-Dumenil, A.M., Overkleeft, H.S., Weber, E., Kalbacher, H., Driessen, C. , Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells, European Journal of Immunology, vol. 32, no. 12, pp. 3348-3357.
Lennon-Dumenil, A.M., Roberts, R.A., Valentijn, K., Driessen, C., Overkleeft, H.S., Erickson, A., Peters, P.J., Bikoff, E., Ploegh, H.L., Bryant, P.W. , The p41 isoform of invariant chain is a chaperone for cathepsin L, Embo Journal, vol. 20, no. 15, pp. 4055-4064.