All journal publications (1963-2013)

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2012
van Noort, G.J.V., van Delft, P., Meeuwenoord, N.J., Overkleeft, H.S., van der Marel, G.A., Filippov, D.V. , Fully automated sequential solid phase approach towards viral RNA-nucleopeptides, Chemical Communications, vol. 48, no. 65, pp. 8093-8095.
2010
Nuzzolo, M., Grabulosa, A., Slawin, A.M.Z., Meeuwenoord, N.J., van der Marel, G.A., Kamer, P.C.J. , Functionalization of Mono- and Oligonucleotides with Phosphane Ligands by Amide Bond Formation, European Journal of Organic Chemistry, no. 17, pp. 3229-3236. DOI
2009
Khan, S., Weterings, J.J., Britten, C.M., de Jong, A.R., Graafland, D., Melief, C.J.M., van der Burg, S.H., van der Marel, G., Overkleeft, H.S., Filippov, D.V., Ossendorp, F. , Chirality of TLR-2 ligand Pam(3)CysSK(4) in fully synthetic peptide conjugates critically influences the induction of specific CD8(+) T-cells, Molecular Immunology, vol. 46, no. 6, pp. 1084-1091. DOI
2008
Malta, E., Verhagen, C.P., Moolenaar, G.F., Filippov, D.V., van der Marel, G.A., Goosen, N. , Functions of base flipping in E. coli nucleotide excision repair, DNA Repair, vol. 7, no. 10, pp. 1647-1658. DOI
Ghisaidoobe, A.B.T., de Koning, M.C., Duynstee, H. I, Ten Kortenaar, P.B.W., Overkleeft, H.S., Filippov, D.V., van der Marel, G.A. , A two-step sulfurization for efficient solution-phase synthesis of phosphorothioate oligonucleotides, Tetrahedron Letters, vol. 49, no. 19, pp. 3129-3132. DOI
2007
Khan, S., Bijker, M.S., Weterings, J.J., Tanke, H.J., Adema, G.J., van Hall, T., Drijfhout, J.W., Melief, C.J.M., Overkleeft, H.S., van der Marel, G.A., Filippov, D.V., van der Burg, S.H., Ossendorp, F. , Distinct uptake mechanisms but similar intracellular processing of two different Toll-like receptor ligand-peptide conjugates in dendritic cells, Journal of Biological Chemistry, vol. 282, no. 29, pp. 21145-21159. DOI
2006
de Koning, M.C., Petersen, L., Weterings, J.J., Overhand, M., van der Marel, G.A., Filippov, D.V. , Synthesis of thiol-modified peptide nucleic acids designed for post-assembly conjugation reactions, Tetrahedron, vol. 62, no. 14, pp. 3248-3258. DOI
2005
van Zutphen, S., Kraus, M., Driessen, C., van der Marel, G.A., Overkleeft, H.S., Reedijk, J. , Probing the potential of platinum(II) complexes for the inhibition of thiol-dependent enzymatic activity, Journal of Inorganic Biochemistry, vol. 99, no. 6, pp. 1384-1389.
2004
Petersen, L., de Koning, M.C., van Kuik-Romeijn, P., Weterings, J., Pol, C.J., Platenburg, G., Overhand, M., van der Marel, G.A., van Boom, J.H. , Synthesis and in vitro evaluation of PNA-peptide-DETA conjugates as potential cell penetrating artificial ribonucleases, Bioconjugate Chemistry, vol. 15, no. 3, pp. 576-582.
de Koning, M.C., Filippov, D.V., van der Marel, G.A., van Boom, J.H., Overhand, M. , Synthesis of peptide-PNA-peptide conjugates by semi-solid-phase chemical ligation combined with deactivation/capture of excess reactants, European Journal of Organic Chemistry, no. 4, pp. 850-857.
2003
Paul, A.V., Peters, J., Mugavero, J., Yin, J., van Boom, J.H., Wimmer, E. , Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus, Journal of Virology, vol. 77, no. 2, pp. 891-904.
2002
Ouwerkerk, N., Steenweg, M., de Ruijter, M., Brouwer, J., van Boom, J.H., Lugtenburg, J., Raap, J. , One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides, Journal of Organic Chemistry, vol. 67, no. 5, pp. 1480-1489.
Sabatini, R., Meeuwenoord, N., van Boom, J.H., Borst, P. , Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA - Evidence for both major and minor groove contacts, Journal of Biological Chemistry, vol. 277, no. 31, pp. 28150-28156.
2001
Borodovsky, A., Kessler, B.M., Casagrande, R., Overkleeft, H.S., Wilkinson, K.D., Ploegh, H.L. , A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14, Embo Journal, vol. 20, no. 18, pp. 5187-5196.
2000
Paul, A.V., Rieder, E., Kim, D.W., van Boom, J.H., Wimmer, E. , Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg, Journal of Virology, vol. 74, no. 22, pp. 10359-10370.
Ouwerkerk, N., van Boom, J.H., Lugtenburg, J., Raap, J. , Chemo-enzymatic synthesis of thymidine C-13-labelled in the 2 '-deoxyribose moiety, European Journal of Organic Chemistry, no. 5, pp. 861-866.
Schmidt, K.S., Sigel, R.K.O., Filippov, D.V., van der Marel, G.A., Lippert, B., Reedijk, J. , Hydrogen bonding between adenine and 2,4-difluorotoluene is definitely not present, as shown by concentration-dependent NMR studies, New Journal of Chemistry, vol. 24, no. 4, pp. 195-197.
Verheijen, J.C., Deiman, B.A.L.M., Yeheskiely, E., van der Marel, G.A., van Boom, J.H. , Efficient hydrolysis of RNA by a PNA-diethylenetriamine adduct, Angewandte Chemie-International Edition, vol. 39, no. 2, pp. 369-+.
Robillard, M.S., Valentijn, A.R.P.M., Meeuwenoord, N.J., van der Marel, G.A., van Boom, J.H., Reedijk, J. , The first solid-phase synthesis of a peptide-tethered platinum(II) complex, Angewandte Chemie-International Edition, vol. 39, no. 17, pp. 3096-3099.
1999
Cohen, L.H., Pieterman, E., van Leeuwen, R.E.W., Du, J.R., Negre-Aminou, P., Valentijn, A.R.P.M., Overhand, M., van der Marel, G.A., van Boom, J.H. , Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein : farnesyl transferase, Biochemical Pharmacology, vol. 57, no. 4, pp. 365-373.
1998
Katano, K., An, H.Y., Aoyagi, Y., Overhand, M., Sucheck, S.J., Stevens, W.C., Hess, C.D., Zhou, X., Hecht, S.M. , Total synthesis of bleomycin group antibiotics. Total syntheses of bleomycin demethyl A(2), bleomycin A(2), and decarbamoyl bleomycin demethyl A(2), Journal of the American Chemical Society, vol. 120, no. 44, pp. 11285-11296.
Paul, A.V., van Boom, J.H., Filippov, D., Wimmer, E. , Protein-primed RNA synthesis by purified poliovirus RNA polymerase, Nature, vol. 393, no. 6682, pp. 280-284.
van der Laan, A.C., van Amsterdam, I, Tesser, G. I, van Boom, J.H., Kuyl-Yeheskiely, E. , Synthesis of chirally pure ornithine based PNA analogues, Nucleosides & Nucleotides, vol. 17, no. 1-3, pp. 219-231.
Gee, J.E., Robbins, I, Van der Laan, A.C., Van Boom, J.H., Colombier, C., Leng, M., Raible, A.M., Nelson, J.S., Lebleu, B. , Assessment of high-affinity hybridization, RNase H cleavage, and covalent linkage in translation arrest by antisense oligonucleotides, Antisense & Nucleic Acid Drug Development, vol. 8, no. 2, pp. 103-111.
1997
vanderLaan, A.C., Brill, R., Kuimelis, R.G., KuylYeheskiely, E., vanBoom, J.H., Andrus, A., Vinayak, R. , A convenient automated solid-phase synthesis of PNA-(5')-DNA-(3')-PNA chimera, Tetrahedron Letters, vol. 38, no. 13, pp. 2249-2252.
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