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A
Ali, A., van den Berg, R.J.B.H.N., Overkleeft, H.S., van der Marel, G.A., Codee, J.D.C. , The methylsulfonylethoxymethyl (Msem) as a hydroxyl protecting group in oligosaccharide synthesis, Tetrahedron, vol. 66, no. 32, pp. 6121-6132. DOI
Ali, A., van den Berg, R., Overkleeft, H.S., Filippov, D.V., van der Marel, G.A., Codee, J.D.C. , Methylsulfonylethoxycarbonyl (Msc) and fluorous propylsulfonylethoxycarbonyl (FPsc) as hydroxy-protecting groups in carbohydrate chemistry, Tetrahedron Letters, vol. 50, no. 19, pp. 2185-2188. DOI
B
Bonger, K.M., van den Berg, R., Knijnenburg, A.D., Heitman, L.H., van Koppen, C.J., Timmers, C.M., Overkleeft, H.S., van der Marel, G.A. , Discovery of Selective Luteinizing Hormone Receptor Agonists Using the Bivalent Ligand Method, Chemmedchem, vol. 4, no. 7, pp. 1189-1195. DOI
Bonger, K.M., van den Berg, R.J.B.H.N., Knijnenburg, A.D., Heitman, L.H., IJzerman, A.P., Oosterom, J., Timmers, C.M., Overkleeft, H.S., van der Marel, G.A. , Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene core, Bioorganic & Medicinal Chemistry, vol. 16, no. 7, pp. 3744-3758. DOI
Bonger, K.M., van den Berg, R.J.B.H.N., Heitman, L.H., IJzerman, A.P., Oosterom, J., Timmers, C.M., Overkleeft, H.S., van der Marel, G.A. , Synthesis and evaluation of homo-bivalent GnRHR ligands, Bioorganic & Medicinal Chemistry, vol. 15, no. 14, pp. 4841-4856. DOI
G
Ghisaidoobe, A., Bikker, P., de Bruijn, A.C.J., Godschalk, F.D., Rogaar, E., Guijt, M.C., Hagens, P., Halma, J.M., van't Hart, S.M., Luitjens, S.B., van Rixel, V.H.S., Wijzenbroek, M., Zweegers, T., Donker-Koopman, W.E., Strijland, A., Boot, R., van der Marel, G., Overkleeft, H.S., Aerts, J., van den Berg, R. , Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated Iminosugars, Acs Medicinal Chemistry Letters, vol. 2, no. 2, pp. 119-123. DOI
J
Janssen, K.G.H., Li, J., Hoang, H.T., Vulto, P., van den Berg, R.J.B.H.N., Overkleeft, H.S., Eijkel, J.C.T., Tas, N.R., van der Linden, H.J., Hankemeier, T. , Limits of miniaturization: Assessing ITP performance in sub-micron and nanochannels, Lab on a Chip, vol. 12, no. 16, pp. 2888-2893. DOI
L
Litjens, R.E.J.N., van den Bos, L.J., Codee, J.D.C., van den Berg, R.J.B.H.N., Overkleeft, H.S., van der Marel, G.A. , Sulfonium triflate mediated glycosidations of aryl 2-azido-2-deoxy-1-thio-D-mannosides, European Journal of Organic Chemistry, no. 5, pp. 918-924.
Litjens, R.E.J.N., Hoogerhout, P., Filippov, D.V., Codee, J.D.C., van den Bos, L.J., van den Berg, R.J.B.H.N., Overkleeft, H.S., van der Marel, G.A. , Synthesis of an alpha-Gal epitope alpha-D-Galp-(1 -> 3)-beta-D-Galp-(1 -> 4)-beta-D-Glcp NAc-lipid conjugate, Journal of Carbohydrate Chemistry, vol. 24, no. 7, pp. 755-769.
R
Risseeuw, M.D.P., van den Berg, R., Donker-Koopman, W.E., van der Marel, G.A., Aerts, J., Overhand, M., Overkleeft, H.S. , Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors, Bioorganic & Medicinal Chemistry Letters, vol. 19, no. 23, pp. 6600-6603. DOI
T
Tuin, A.W., Mol, M.A.E., van den Berg, R.M., Fidder, A., van der Marel, G.A., Overkleeft, H.S., Noort, D. , Activity-Based Protein Profiling Reveals Broad Reactivity of the Nerve Agent Sarin, Chemical Research in Toxicology, vol. 22, no. 4, pp. 683-689. DOI
V
van den Nieuwendijk, A.M.C.H., van den Berg, R.J.B.H.N., Ruben, M., Witte, M.D., Brussee, J., Boot, R.G., van der Marel, G.A., Aerts, J.M.F.G., Overkleeft, H.S. , Synthesis of Eight 1-Deoxynojirimycin Isomers from a Single Chiral Cyanohydrin, European Journal of Organic Chemistry, no. 18, pp. 3437-3446. DOI
van den Berg, R.J.B.H.N., Wennekes, T., Ghisaidoobe, A., Donker-Koopman, W.E., Strijland, A., Boot, R.G., van der Marel, G.A., Aerts, J.M.F.G., Overkleeft, H.S. , Assessment of Partially Deoxygenated Deoxynojirimycin Derivatives as Glucosylceramide Synthase Inhibitors, Acs Medicinal Chemistry Letters, vol. 2, no. 7, pp. 519-522. DOI
van Scherpenzeel, M., van den Berg, R., Donker-Koopman, W.E., Liskamp, R.M.J., Aerts, J., Overkleeft, H.S., Pieters, R.J. , Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase, Bioorganic & Medicinal Chemistry, vol. 18, no. 1, pp. 267-273. DOI
van den Nieuwendijk, A.M.C.H., Ruben, M., Engelsma, S.E., Risseeuw, M.D.P., van den Berg, R.J.B.H.N., Boot, R.G., Aerts, J.M., Brussee, J., van der Marel, G.A., Overkleeft, H.S. , Synthesis of L-altro-1-deoxynojirimycin, D-allo-1-deoxynojirimycin and D-galacto-1-deoxynojirimycin from a single chiral cyanohydrin, Organic Letters, vol. 12, pp. 3957-3959.
van den Berg, R.J.B.H.N., Boltje, T.J., Verhagen, C.P., Litjens, R.E.J.N., van der Marel, G.A., Overkleeft, H.S. , An efficient synthesis of the natural tetrahydrofuran pachastrissamine starting from D-ribo-phytosphingosine, Journal of Organic Chemistry, vol. 71, no. 2, pp. 836-839.
van den Bos, L.J., Litjens, R.E.J.N., van den Berg, R.J.B.H.N., Overkleeft, H.S., van der Marel, G.A. , Preparation of 1-thio uronic acid lactones and their use in oligosaccharide synthesis, Organic Letters, vol. 7, no. 10, pp. 2007-2010.
van den Berg, R.J.B.H.N., Donker-Koopman, W., van Boom, J.H., Aerts, H.M.F.G., Noort, D. , Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal beta-hexosaminidases, Bioorganic & Medicinal Chemistry, vol. 12, no. 5, pp. 891-902.
van den Berg, R.J.B.H.N., Korevaar, C.G.N., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , Effective, high-yielding, and stereospecific total synthesis of D-erythro-(2R,3S)-sphingosine from D-ribo-(2S,3S,4R)-phytosphingosine, Journal of Organic Chemistry, vol. 69, no. 17, pp. 5699-5704.
van den Berg, R.J.B.H.N., Korevaar, C.G.N., van der Marel, G.A., Overkleeft, H.S., van Boom, J.H. , A simple and low cost synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine: glycosphingolipid precursors, Tetrahedron Letters, vol. 43, no. 46, pp. 8409-8412.
van den Berg, R.J.B.H.N., Noort, D., van der Marel, G.A., van Boom, J.H., Benschop, H.P. , Synthesis of pseudo-disaccharide analogues of lipid A: Haptens for the generation of antibodies with glycosidase activity towards lipid A, Journal of Carbohydrate Chemistry, vol. 21, no. 3, pp. 167-188.
van den Berg, R.J.B.H.N., Noort, D., Milder-Enacache, E.S., van der Marel, G.A., van Boom, J.H., Benschop, H.P. , Approach toward a generic treatment of Gram-negative infections: Synthesis of haptens for catalytic antibody mediated cleavage of the interglycosidic bond in lipid A, European Journal of Organic Chemistry, no. 10, pp. 2593-2600.
W
Wennekes, T., Bonger, K.M., Vogel, K., van den Berg, R.J.B.H.N., Strijland, A., Donker-Koopman, W.E., Aerts, J.M.F.G., van der Marel, G.A., Overkleeft, H.S. , The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction, European Journal of Organic Chemistry, no. 32, pp. 6420-6454.
Wennekes, T., van den Berg, R., Boltje, T.J., Donker-Koopman, W.E., Kuijper, B., van der Marel, G.A., Strijland, A., Verhagen, C.P., Aerts, J., Overkleeft, H.S. , Synthesis and Evaluation of Lipophilic Aza-C-glycosides as Inhibitors of Glucosylceramide Metabolism, European Journal of Organic Chemistry, no. 7, pp. 1258-1283. DOI
Wennekes, T., Meijer, A.J., Groen, A.K., Boot, R.G., Groener, J.E., van Eijk, M., Ottenhoff, R., Bijl, N., Ghauharali, K., Song, H., O'Shea, T.J., Liu, H.L., Yew, N., Copeland, D., van den Berg, R.J., van der Marel, G.A., Overkleeft, H.S., Aerts, J.M. , Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation, Journal of Medicinal Chemistry, vol. 53, no. 2, pp. 689-698. DOI
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