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2012
van den Nieuwendijk, A.M.C.H., van den Berg, R.J.B.H.N., Ruben, M., Witte, M.D., Brussee, J., Boot, R.G., van der Marel, G.A., Aerts, J.M.F.G., Overkleeft, H.S. , Synthesis of Eight 1-Deoxynojirimycin Isomers from a Single Chiral Cyanohydrin, European Journal of Organic Chemistry, no. 18, pp. 3437-3446. DOI
Kallemeijn, W.W., Li, K.Y., Witte, M.D., Marques, A.R.A., Aten, J., Scheij, S., Jiang, J.B., Willems, L. I, Voorn-Brouwer, T.M., van Roomen, C.P.A.A., Ottenhoff, R., Boot, R.G., van den Elst, H., Walvoort, M.T.C., Florea, B. I, Codee, J.D.C., van der Marel, G.A., Aerts, J.M.F.G., Overkleeft, H.S. , Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining beta-Exoglucosidases In Situ and In Vivo, Angewandte Chemie-International Edition, vol. 51, no. 50, pp. 12529-12533.
Walvoort, M.T.C., Kallemeijn, W.W., Willems, L. I, Witte, M.D., Aerts, J.M.F.G., van der Marel, G.A., Codee, J.D.C., Overkleeft, H.S. , Tuning the leaving group in 2-deoxy-2-fluoroglucoside results in improved activity-based retaining beta-glucosidase probes, Chemical Communications, vol. 48, no. 84, pp. 10386-10388.
2011
Witte, M.D., Walvoort, M.T., Li, K.Y., Kallemeijn, W.W., Donker-Koopman, W.E., Boot, R.G., Aerts, J.M., Codee, J.D., van der Marel, G.A., Overkleeft, H.S. , Activity-Based Profiling of Retaining beta-Glucosidases: A Comparative Study, Chembiochem, vol. 12, no. 8, pp. 1263-9. DOI
Aerts, J.M., Kallemeijn, W.W., Wegdam, W., Joao Ferraz, M., van Breemen, M.J., Dekker, N., Kramer, G., Poorthuis, B.J., Groener, J.E., Cox-Brinkman, J., Rombach, S.M., Hollak, C.E., Linthorst, G.E., Witte, M.D., Gold, H., van der Marel, G.A., Overkleeft, H.S., Boot, R.G. , Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies, J Inherit Metab Dis, vol. 34, issue 3, pp. 99-119. DOI
Aerts, J.M.F.G., Kallemeijn, W.W., Wegdam, W., Ferraz, M.J., van Breemen, M.J., Dekker, N., Kramer, G., Poorthuis, B.J., Groener, J.E.M., Cox-Brinkman, J., Rombach, S.M., Hollak, C.E.M., Linthorst, G.E., Witte, M.D., Gold, H., van der Marel, G.A., Overkleeft, H.S., Boot, R.G. , Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies, Journal of Inherited Metabolic Disease, vol. 34, no. 3, pp. 605-619. DOI
Walvoort, M.T.C., de Witte, W., van Dijk, J., Dinkelaar, J., Lodder, G., Overkleeft, H.S., Codee, J.D.C., van der Marel, G.A. , Mannopyranosyl Uronic Acid Donor Reactivity, Organic Letters, vol. 13, no. 16, pp. 4360-4363. DOI
Witte, M.D., van der Marel, G.A., Aerts, J.M.F.G., Overkleeft, H.S. , Irreversible inhibitors and activity-based probes as research tools in chemical glycobiology, Organic & Biomolecular Chemistry, vol. 9, no. 17, pp. 5908-5926. DOI
Geurink, P.P., Florea, B. I, Li, N., Witte, M.D., Verasdonck, J., Kuo, C.L., van der Marel, G.A., Overkleeft, H.S. , A levulinoyl ester based cleavable linker for activity-based protein profiling, Angewandte Chemie, International Edition, pp. in press.
2010
Geurink, P.P., Florea, B. I, Li, N., Witte, M.D., Verasdonck, J., Kuo, C.L., van der Marel, G.A., Overkleeft, H.S. , A Cleavable Linker Based on the Levulinoyl Ester for Activity-Based Protein Profiling, Angewandte Chemie-International Edition, vol. 49, no. 38, pp. 6802-6805. DOI
Witte, M.D., Kallemeijn, W.W., Aten, J., Li, K.Y., Strijland, A., Donker-Koopman, W.E., van den Nieuwendijk, A., Bleijlevens, B., Kramer, G., Florea, B. I, Hooibrink, B., Hollak, C.E.M., Ottenhoff, R., Boot, R.G., van der Marel, G.A., Overkleeft, H.S., Aerts, J. , Ultrasensitive in situ visualization of active glucocerebrosidase molecules, Nature Chemical Biology, vol. 6, no. 12, pp. 907-913. DOI
2009
Witte, M.D., Florea, B. I, Verdoes, M., Adeyanju, O., Van der Marel, G.A., Overkleeft, H.S. , O-GlcNAc Peptide Epoxyketones Are Recognized by Mammalian Proteasomes, Journal of the American Chemical Society, vol. 131, no. 34, pp. 12064-+. DOI
Witte, M.D., Horst, D., Wiertz, E.J., van der Marel, G.A., Overkleeft, H.S. , Synthesis and biological evaluation of a chitobiose-based peptide N-glycanase inhibitor library, J Org Chem, vol. 74, no. 2, pp. 605-16. DOI
2007
Witte, M.D., Descals, C.V., de Lavoir, S.V., Florea, B. I, van der Marel, G.A., Overkleeft, H.S. , Bodipy-VAD-Fmk, a useful tool to study yeast peptide N-glycanase activity, Org Biomol Chem, vol. 5, no. 22, pp. 3690-7. DOI
2006
Verdoes, M., Florea, B. I, Menendez-Benito, V., Maynard, C.J., Witte, M.D., Van der Linden, W.A., Van den Nieuwendijk, A.M.C.H., Hofmann, T., Berkers, C.R., van Leeuwen, F.W.B., Groothuis, T.A., Leeuwenburgh, M.A., Ovaa, H., Neefjes, J.J., Filippov, D.V., van der Marel, G.A., Dantuma, N.P., Overkleeft, H.S. , A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo, Chemistry & Biology, vol. 13, no. 11, pp. 1217-1226. DOI
Dinkelaar, J., Witte, M.D., van den Bos, L.J., Overkleeft, H.S., van der Marel, G.A. , NIS/TFA: a general method for hydrolyzing thioglycosides, Carbohydrate Research, vol. 341, no. 10, pp. 1723-1729.
Risseeuw, M.D.P., Grotenbreg, G.M., Witte, M.D., Tuin, A.W., Leeuwenburgh, M.A., Van der Marl, G.A., Overkleeft, H.S., Overhand, M. , The synthesis of cis- and trans-fused bicyclic sugar amino acids, European Journal of Organic Chemistry, no. 17, pp. 3877-3886.
2005
Grotenbreg, G.M., Witte, M.D., van Hooft, P.A.V., Spalburg, E., Reiss, P., Noort, D., de Neeling, A.J., Koert, U., van der Marel, G.A., Overleeft, H.S., Overhand, M. , Synthesis and biological evaluation of gramicidin S dimers, Organic & Biomolecular Chemistry, vol. 3, no. 2, pp. 233-238.
2004
Grotenbreg, G.M., Tuin, A.W., Witte, M.D., Leeuwenburgh, M.A., van Boom, J.H., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , An expeditious route towards pyranopyran sugar amino acids, Synlett, no. 5, pp. 904-906.