All journal publications (1963-2013)

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2006
Filippov, D.V., Welters, M.J.P., Valentijn, A.R.P.M., Melief, C.J.M., van der Marel, G.A., van der Burg, S.H., Overkleeft, H.S., Drijfhout, J.W. , Chemical synthesis of the HPV16 E7 protein, Tetrahedron Letters, vol. 47, no. 52, pp. 9349-9352. DOI
2004
Welters, M.J.P., Filippov, D.V., van den Eeden, S.J.F., Franken, K.L.M.C., Nouta, J., Valentijn, A.R.P.M., van der Marel, G.A., Overkleeft, H.S., Lipford, G., Offringa, R., Melief, C.J.M., van Boom, J.H., van der Burg, S.H., Drijfhout, J. , Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model, Vaccine, vol. 23, no. 3, pp. 305-311.
2003
Kriek, N.M.A.J., van der Hout, E., Kelly, P., van Meijgaarden, K.E., Geluk, A., Ottenhoff, T.H.M., van der Marel, G.A., Overhand, M., van Boom, J.H., Valentijn, A.R.P.M., Overkleeft, H.S. , Synthesis of novel tetrahydropyran-based dipeptide isosters by Overman rearrangement of 2,3-didehydroglycosides, European Journal of Organic Chemistry, no. 13, pp. 2418-2427.
2002
Biessen, E.A.L., Sliedregt-Bol, K., Hoen, P.A.C.T., Prince, P., Van der Bilt, E., Valentijn, A.R.P.M., Meeuwenoord, N.J., Princen, H., Bijsterbosch, M.K., Van der Marel, G.A., Van Boom, J.H., Van Berkel, T.J.C. , Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes, Bioconjugate Chemistry, vol. 13, no. 2, pp. 295-302.
2001
Sliedregt, L.A.J.M., van Rossenberg, S.M.W., Autar, R., Valentijn, A.R.P.M., van der Marel, G.A., van Boom, J.H., Piperi, C., van der Merwe, P.A., Kuiper, J., van Berkel, T.J.C., Biessen, E.A.L. , Design and synthesis of a multivalent homing device for targeting to murine CD22, Bioorganic & Medicinal Chemistry, vol. 9, no. 1, pp. 85-97.
Lennon-Dumenil, A.M., Roberts, R.A., Valentijn, K., Driessen, C., Overkleeft, H.S., Erickson, A., Peters, P.J., Bikoff, E., Ploegh, H.L., Bryant, P.W. , The p41 isoform of invariant chain is a chaperone for cathepsin L, Embo Journal, vol. 20, no. 15, pp. 4055-4064.
2000
Biessen, E.A.L., Valentijn, A.R.P.M., De Vrueh, R.L.A., Van de Bilt, E., Sliedregt, L.A.J.M., Prince, P., Bijsterbosch, M.K., Van Boom, J.H., Van der Marel, G.A., Abrahams, P.J., Van Berkel, T.J.C. , Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity, Faseb Journal, vol. 14, no. 12, pp. 1784-1792.
de Kort, M., Regenbogen, A.D., Valentijn, A.R.P.M., Challiss, R.A.J., Iwata, Y., Miyamoto, S., van der Marcel, G.A., van Boom, J.H. , Spirophostins: Conformationally restricted analogues of adenophostin A, Chemistry-a European Journal, vol. 6, no. 15, pp. 2696-2704.
de Kort, M., Correa, V., Valentijn, A.R.P.M., van der Marel, G.A., Potter, B.V.L., Taylor, C.W., van Boom, J.H. , Synthesis of potent agonists of the D-myo-inositol 1,4,5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A, Journal of Medicinal Chemistry, vol. 43, no. 17, pp. 3295-3303.
Robillard, M.S., Valentijn, A.R.P.M., Meeuwenoord, N.J., van der Marel, G.A., van Boom, J.H., Reedijk, J. , The first solid-phase synthesis of a peptide-tethered platinum(II) complex, Angewandte Chemie-International Edition, vol. 39, no. 17, pp. 3096-3099.
1999
Biessen, E.A.L., van de Bilt, E., Prince, P., Valentijn, R., Van de Marel, G.A., Van Boom, J.H., Van Berkel, T.J.C. , Tissue-specific down-regulation of microsomal triglyceride transfer protein by glycoconjugated PNA, Circulation, vol. 100, no. 18, pp. 815-816.
Sliedregt, L.A.J.M., Rensen, P.C.N., Rump, E.T., van Santbrink, P.J., Bijsterbosch, M.K., Valentijn, A.R.P.M., van der Marel, G.A., van Boom, J.H., van Berkel, T.J.C., Biessen, E.A.L. , Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor, Journal of Medicinal Chemistry, vol. 42, no. 4, pp. 609-618.
Cohen, L.H., Pieterman, E., van Leeuwen, R.E.W., Du, J.R., Negre-Aminou, P., Valentijn, A.R.P.M., Overhand, M., van der Marel, G.A., van Boom, J.H. , Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein : farnesyl transferase, Biochemical Pharmacology, vol. 57, no. 4, pp. 365-373.
van Delft, F.L., Valentijn, A.R.P.M., van der Marel, G.A., van Boom, J.H. , Preparation of 2,5-anhydrohexitols - (Part I). Silicon-directed stereocontrolled cyclization, Journal of Carbohydrate Chemistry, vol. 18, no. 2, pp. 165-190.
van Delft, F.L., Valentijn, A.R.P.M., van der Marel, G.A., van Boom, J.H. , Preparation of 2,5-anhydrohexitols - (Part II). Intramolecular nucleophilic substitution of cyclic sulfates, Journal of Carbohydrate Chemistry, vol. 18, no. 2, pp. 191-207.
1998
Overhand, M., Stuivenberg, H.R., Pieterman, E., Cohen, L.H., van Leeuwen, R.E.W., Valentijn, A.R.P.M., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , Inhibitors of protein : farnesyl transferase and protein : geranylgeranyl transferase I: Synthesis of homologous diphosphonate analogs of isoprenylated pyrophosphate, Bioorganic Chemistry, vol. 26, no. 5, pp. 269-282.
1997
Overhand, M., Pieterman, E., Cohen, L.H., Valentijn, A.R.P.M., vanderMarel, G.A., vanBoom, J.H. , Synthesis of triphosphonate analogues of farnesyl pyrophosphate. Inhibitors of squalene synthase and protein:farnesyl transferase, Bioorganic & Medicinal Chemistry Letters, vol. 7, no. 18, pp. 2435-2440.
deKort, M., Valentijn, A.R.P.M., vanderMarel, G.A., vanBoom, J.H. , Synthesis of clustered disaccharide polyphosphate analogues of adenophostin A, Tetrahedron Letters, vol. 38, no. 43, pp. 7629-7632.
Valentijn, A.R.P.M., vanderMarel, G.A., Sliedregt, L.A.J.M., vanBerkel, T.J.C., Biessen, E.A.L., vanBoom, J.H. , Solid-phase synthesis of lysine-based cluster galactosides with high affinity for the asialoglycoprotein receptor, Tetrahedron, vol. 53, no. 2, pp. 759-770.
1996
Wijsman, E.R., Filippov, D., Valentijn, A., vanderMarel, G.A., vanBoom, J.H. , Solid-support synthesis of di- and tetramannosylated tetrathymidylic acid, Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands Chemical Society, vol. 115, no. 9, pp. 397-&.
Wijsman, E.R., Filippov, D., Valentijn, A.R.P.M., vanderMarel, G.A., vanBoom, J.H. , Solid-support synthesis of di- and tetramannosylated tetrathymidylic acid, Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands Chemical Society, vol. 115, no. 9, pp. 397-&.
1995
Cohen, L.H., Valentijn, A., Roodenburg, L., Vanleeuwen, R.E.W., Huisman, R.H., Lutz, R.J., Vandermarel, G.A., Vanbooms, J.H. , Different Analogs of Farnesyl Pyrophosphate Inhibit Squalene Synthase and Protein-Farnesyltransferase to Different Extents, Biochemical Pharmacology, vol. 49, no. 6, pp. 839-845.
Valentijn, A.R.P.M., Dehaan, R., Hagens, S., Dekant, E., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , Synthesis of a Potential Enzyme-Specific Inhibitor of Squalene Synthase, Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands Chemical Society, vol. 114, no. 7, pp. 332-336.
Valentijn, A.R.P.M., Vandenberg, O., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , Synthesis of Pyrophosphonic Acid Analogs of Farnesyl Pyrophosphate, Tetrahedron, vol. 51, no. 7, pp. 2099-2108.
Valentijn, A.R.P.M., Broxterman, H.J.G., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , Synthesis of 1,6-Anhydro-2,3-Di-O-Farnesyl-5-O-([(Phosphonomethyl)Phosphinyl]Methyl)-Alpha-D-Galactofuranose - a Zaragozic Acid - Presqualene Pyrophosphate Hybrid, Journal of Carbohydrate Chemistry, vol. 14, no. 6, pp. 737-749.
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