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2014
Liu, W.M., Skinner, S.P., Timmer, M., Blok, A., Hass, M.A.S., Filippov, D.V., Overhand, M., Ubbink, M. , A Two-Armed Lanthanoid-Chelating Paramagnetic NMR Probe Linked to Proteins via Thioether Linkages, Chemistry-a European Journal, vol. 20, no. 21, pp. 6256-6258. DOI
Nabuurs, R.J., Kapoerchan, V.V., Metaxas, A., de Jongh, S., de Backer, M., Welling, M.M., Jiskoot, W., Windhorst, A.D., Overkleeft, H.S., van Buchem, M.A., Overhand, M., van der Weerd, L. , Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands, Bioorganic & Medicinal Chemistry, vol. 22, no. 8, pp. 2469-81. DOI
2013
Risseeuw, M., Overhand, M., Fleet, G.W.J., Simone, M. I , A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues, Amino Acids, vol. 45, no. 4, pp. 613-689. DOI
Otero, J.M., van der Knaap, M., Llamas-Saiz, A.L., van Raaij, M.J., Amorin, M., Granja, J.R., Filippov, D.V., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Design, Synthesis, and Structural Analysis of Turn Modified cyclo-(alpha beta(3)alpha beta(2)alpha)(2) Peptide Derivatives toward Crystalline Hexagon-Shaped Cationic Nanochannel Assemblies, Crystal Growth & Design, vol. 13, no. 10, pp. 4355-4367. DOI
Luo, J.H., Otero, J.M., Yu, C.H., Warmlander, S.K.T.S., Graslund, A., Overhand, M., Abrahams, J.P. , Inhibiting and Reversing Amyloid-beta Peptide (1-40) Fibril Formation with Gramicidin S and Engineered Analogues, Chemistry-a European Journal, vol. 19, no. 51, pp. 17338-17348. DOI
Guisado-Barrios, G., Munoz, B.K., Kamer, P.C.J., Lastdrager, B., van der Marel, G., Overhand, M., Vega-Vazquez, M., Martin-Pastor, M. , Cyclic decapeptide gramicidin S derivatives containing phosphines: novel ligands for asymmetric catalysis, Dalton Transactions, vol. 42, no. 6, pp. 1973-1978. DOI
2012
Liu, W.M., Keizers, P.H.J., Hass, M.A.S., Blok, A., Tirnmer, M., Sarris, A.J.C., Overhand, M., Ubbink, M. , A pH-Sensitive, Colorful, Lanthanide-Chelating Paramagnetic NMR Probe, Journal of the American Chemical Society, vol. 134, no. 41, pp. 17306-17313.
Kapoerchan, V.V., Knijnenburg, A.D., Keizer, P., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., Otero, J.M., Llamas-Saiz, A.L., van Raaij, M.J., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , 'Inverted' analogs of the antibiotic gramicidin S with an improved biological profile, Bioorganic & Medicinal Chemistry, vol. 20, no. 20, pp. 6059-6062.
van der Knaap, M., Basalan, F., van de Mei, H.C., Busscher, H.J., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Synthesis and Biological Evaluation of Gramicidin S-Inspired Cyclic Mixed a/ss-Peptides, Chemistry & Biodiversity, vol. 9, no. 11, pp. 2494-2506.
van der Knaap, M., Otero, J.M., Llamas-Saiz, A., van Raaij, M.J., Lageveen, L. I, Busscher, H.J., Grotenbreg, G.M., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Design, synthesis and structural analysis of mixed alpha/beta-peptides that adopt stable cyclic hairpin-like conformations, Tetrahedron, vol. 68, no. 10, pp. 2391-2400. DOI
Knijnenburg, A.D., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., Grotenbreg, G.M., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Ring-Extended Gramicidin S Analogs Containing cis d-Sugar Amino Acid Turn Mimetics with Varying Ring Size, Helvetica Chimica Acta, vol. 95, no. 12, pp. 2544-2561.
Li, J., Girard, G., Florea, B. I, Geurink, P.P., Li, N., van der Marel, G.A., Overhand, M., Overkleeft, H.S., van Wezel, G.P. , Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach, Organic & Biomolecular Chemistry, vol. 10, no. 43, pp. 8677-8683.
2011
Dasgupta, S., Hu, X., Keizers, P.H.J., Liu, W., Luchinat, C., Nagulapalli, M., Overhand, M., Parigi, G., Sgheri, L., Ubbink, M. , Narrowing the conformational space sampled by two-domain proteins with paramagnetic probes in both domains, Journal of Biomolecular Nmr, vol. 51, no. 3, pp. 253-263. DOI
van der Knaap, M., Lageveen, L.T., Busscher, H.J., Mars-Groenendijk, R., Noort, D., Otero, J.M., Llamas-Saiz, A.L., van Raaij, M.J., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Evaluation of readily accessible azoles as mimics of the aromatic ring of d-phenylalanine in the turn region of gramicidin s, Chemmedchem, vol. 6, no. 5, pp. 840-7. DOI
Knijnenburg, A.D., Tuin, A.W., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., Otero, J.M., Llamas-Saiz, A.L., van Raaij, M.J., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Exploring the conformational and biological versatility of beta-turn-modified gramicidin S by using sugar amino acid homologues that vary in ring size, Chemistry, vol. 17, no. 14, pp. 3995-4004. DOI
Canalle, L.A., van der Knaap, M., Overhand, M., van Hest, J.C.M. , A Comparison of Triazole-forming Bioconjugation Techniques for Constructing Comb-Shaped Peptide Polymer Bioconjugates, Macromolecular Rapid Communications, vol. 32, no. 2, pp. 203-208. DOI
Knijnenburg, A.D., Kapoerchan, V.V., Grotenbreg, G.M., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., Otero, J.M., Llamas-Saiz, A.L., van Raaij, M.J., Ravensbergen, B., Nibbering, P.H., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Synthesis and evaluation of strand and turn modified ring-extended gramicidin S derivatives, Bioorg Med Chem, vol. 19, issue 11, pp. 3402-3409. DOI
2010
Knijnenburg, A.D., Kapoerchan, V.V., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Tuning hydrophobicity of highly cationic tetradecameric Gramicidin S analogues using adamantane amino acids, Bioorg Med Chem, vol. 18, pp. 8403-8409. DOI
Kapoerchan, V.V., Knijnenburg, A.D., Niamat, M., Spalburg, E., de Neeling, A.J., Nibbering, P.H., Mars-Groenendijk, R.H., Noort, D., Otero, J.M., Llamas-Saiz, A.L., van Raaij, M.J., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity, Chemistry - a European Journal, vol. 16, no. 40, pp. 12174-81. DOI
Semrau, S., Monster, M.W.L., van der Knaap, M., Florea, B. I, Schmidt, T., Overhand, M. , Membrane lysis by gramicidin S visualized in red blood cells and giant vesicles, Biochimica Et Biophysica Acta-Biomembranes, vol. 1798, no. 11, pp. 2033-2039. DOI
Kapoerchan, V.V., Wiesner, M., Hillaert, U., Drijfhout, J.W., Overhand, M., Alard, P., van der Marel, G.A., Overkleeft, H.S., Koning, F. , Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule, Molecular Immunology, vol. 47, no. 5, pp. 1091-1097. DOI
Risseeuw, M.D., Florea, B. I, van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors, Bioorg Chem, vol. 38, pp. 202-209. DOI
Kapoerchan, V.V., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., Otero, J.M., Ferraces-Casais, P., Llamas-Saiz, A.L., van Raaij, M.J., van Doorn, J., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Gramicidin S derivatives containing cis- and trans-morpholine amino acids (MAAs) as turn mimetics, Chemistry - a European Journal, vol. 16, no. 14, pp. 4259-65. DOI
2009
Tuin, A.W., Grotenbreg, G.M., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., van der Marel, G.A., Noort, D., Overkleeft, H.S., Overhand, M. , Structural and biological evaluation of some loloatin C analogues, Bioorganic & Medicinal Chemistry, vol. 17, no. 17, pp. 6233-6240. DOI
Tuin, A.W., Palachanis, D.K., Buizert, A., Grotenbreg, G.M., Spalburg, E., de Neeling, A.J., Mars-Groenendijk, R.H., Noort, D., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Synthesis and Biological Evaluation of Novel Gramicidin S Analogues, European Journal of Organic Chemistry, no. 25, pp. 4231-4241. DOI