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2010
Geurink, P.P., Klein, T., Prely, L., Paal, K., Leeuwenburgh, M.A., van der Marel, G.A., Kauffman, H.F., Overkleeft, H.S., Bischoff, R. , Design of Peptide Hydroxamate-Based Photoreactive Activity-Based Probes of Zinc-Dependent Metalloproteases, European Journal of Organic Chemistry, no. 11, pp. 2100-2112. DOI
2009
de Nooijer, R., Bot, I, von der Thusen, J.H., Leeuwenburgh, M.A., Overkleeft, H.S., Kraaijeveld, A.O., Dorland, R., van Santbrink, P.J., van Heiningen, S.H., Westra, M.M., Kovanen, P.T., Jukema, J.W., van der Wall, E.E., van Berkel, T.J., Shi, . , Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis, Arterioscler Thromb Vasc Biol, vol. 29, no. 2, pp. 188-94. DOI
Geurink, P., Klein, T., Leeuwenburgh, M., van der Marel, G., Kauffman, H., Bischoff, R., Overkleeft, H. , A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol, Org Biomol Chem, vol. 6, no. 7, pp. 1244-50. DOI
2008
Geurink, P., Klein, T., Leeuwenburgh, M., van der Marel, G., Kauffman, H., Bischoff, R., Overkleeft, H. , A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol, Organic & Biomolecular Chemistry, vol. 6, no. 7, pp. 1244-1250. DOI
2007
van Swieten, P.F., Samuel, E., Hernandez, R.O., van den Nieuwendijk, A.M.C.H., Leeuwenburgh, M.A., van der Marel, G.A., Kessler, B.M., Overkleeft, H.S., Kisselev, A.F. , A cell-permeable inhilbitor and activity-based probe for the caspase-like activity of the proteasome, Bioorganic & Medicinal Chemistry Letters, vol. 17, no. 12, pp. 3402-3405. DOI
2006
Verdoes, M., Florea, B. I, Menendez-Benito, V., Maynard, C.J., Witte, M.D., Van der Linden, W.A., Van den Nieuwendijk, A.M.C.H., Hofmann, T., Berkers, C.R., van Leeuwen, F.W.B., Groothuis, T.A., Leeuwenburgh, M.A., Ovaa, H., Neefjes, J.J., Filippov, D.V., van der Marel, G.A., Dantuma, N.P., Overkleeft, H.S. , A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo, Chemistry & Biology, vol. 13, no. 11, pp. 1217-1226. DOI
Risseeuw, M.D.P., Grotenbreg, G.M., Witte, M.D., Tuin, A.W., Leeuwenburgh, M.A., Van der Marl, G.A., Overkleeft, H.S., Overhand, M. , The synthesis of cis- and trans-fused bicyclic sugar amino acids, European Journal of Organic Chemistry, no. 17, pp. 3877-3886.
Leeuwenburgh, M.A., Geurink, P.P., Klein, T., Kauffman, H.F., van der Marel, G.A., Bischoff, R., Overkleeft, H.S. , Solid-phase synthesis of succinylhydroxamate peptides: Functionalized matrix metalloproteinase inhibitors, Organic Letters, vol. 8, no. 8, pp. 1705-1708.
2005
van Swieten, P.F., Leeuwenburgh, M.A., Kessler, B.M., Overkleeft, H.S. , Bioorthogonal organic chemistry in living cells: novel strategies for labeling biomolecules, Organic & Biomolecular Chemistry, vol. 3, no. 1, pp. 20-27.
2004
van Swieten, P.F., Maehr, R., van den Nieuwendijk, A.M.C.H., Kessler, B.M., Reich, M., Wong, C.S., Kalbacher, H., Leeuwenburgh, M.A., Driessen, C., van der Marel, G.A., Ploegh, H.L., Overkleeft, H.S. , Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases, Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 12, pp. 3131-3134.
Grotenbreg, G.M., Tuin, A.W., Witte, M.D., Leeuwenburgh, M.A., van Boom, J.H., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , An expeditious route towards pyranopyran sugar amino acids, Synlett, no. 5, pp. 904-906.
van Hooft, P.A.V., El Oualid, F., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H., Leeuwenburgh, M.A. , Synthesis and elaboration of functionalised carbohydrate-derived spiroketals, Organic & Biomolecular Chemistry, vol. 2, no. 9, pp. 1395-1403.
2003
Leeuwenburgh, M.A., van der Marel, G.A., Overkleeft, H.S. , Olefin metathesis in glycobiology: new routes towards diverse neoglycoconjugates, Current Opinion in Chemical Biology, vol. 7, no. 6, pp. 757-765.
Ovaa, H., van Swieten, P.F., Kessler, B.M., Leeuwenburgh, M.A., Fiebiger, E., van den Nieuwendijk, A.M.C.H., Galardy, P.J., van der Marel, G.A., Ploegh, H.L., Overkleeft, H.S. , Chemistry in living cells: Detection of active proteasomes by a two-step labeling strategy, Angewandte Chemie-International Edition, vol. 42, no. 31, pp. 3626-3629.
Leeuwenburgh, M.A., van der Marel, G.A., Overkleeft, H.S., van Boom, J.H. , From alpha-1,2-anhydrosugars to C-glycosides: The influence of Lewis acids and nucleophiles on the stereochemistry, Journal of Carbohydrate Chemistry, vol. 22, no. 7-8, pp. 549-564.
2001
Litjens, R.E.J.N., Leeuwenburgh, M.A., van der Marel, G.A., van Boom, J.H. , A novel approach towards the stereoselective synthesis of 2-azido-2-deoxy-beta-D-mannosides, Tetrahedron Letters, vol. 42, no. 49, pp. 8693-8696.
Turner, J.J., Leeuwenburgh, M.A., van der Marel, G.A., van Boom, J.H. , A convenient route to alpha-amino acids with beta-alkyne substituents from a serine derived aziridine, Tetrahedron Letters, vol. 42, no. 49, pp. 8713-8716.
2000
Leeuwenburgh, M.A., Litjens, R.E.J.N., Codee, J.D.C., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , Radical cyclization of sugar-derived beta-(alkynyloxy)acrylates: Synthesis of novel fused ethers, Organic Letters, vol. 2, no. 9, pp. 1275-1277.
Leeuwenburgh, M.A., Appeldoorn, C.C.M., van Hooft, P.A.V., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , Synthesis of highly functionalised carbohydrate-derived spiroacetals by ring-closing metathesis and Pauson-Khand reaction of ketoglycosidic enynes, European Journal of Organic Chemistry, no. 6, pp. 873-877.
1999
Leeuwenburgh, M.A., Picasso, S., Overkleeft, H.S., van der Marel, G.A., Vogel, P., van Boom, J.H. , A short and flexible route to aza-beta-(1 -> 6)-C-disaccharides: Selective alpha-glycosidase inhibitors, European Journal of Organic Chemistry, no. 5, pp. 1185-1189.
Leeuwenburgh, M.A., Kulker, C., Duynstee, H. I, Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , A convenient route to cis- and trans-fused bicyclic ethers by ruthenium mediated ring-closing metathesis of diene and enyne carbohydrate derivatives, Tetrahedron, vol. 55, no. 27, pp. 8253-8262.
Leeuwenburgh, M.A., Kulker, C., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , Synthesis of a trans-fused tricyclic ether using a novel differentially protected glucal, Synlett, no. 12, pp. 1945-1947.
1998
Ovaa, H., Leeuwenburgh, M.A., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , An expeditious route to the synthesis of highly functionalized chiral oxepines from monosaccharides, Tetrahedron Letters, vol. 39, no. 19, pp. 3025-3028.
Timmers, C.M., Wigchert, S.C.M., Leeuwenburgh, M.A., van der Marel, G.A., van Boom, J.H. , Synthesis of tetrameric arabinogalactans based on 1,2-anhydrosugars, European Journal of Organic Chemistry, no. 1, pp. 91-97.
van Hooft, P.A.V., Leeuwenburgh, M.A., Overkleeft, H.S., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , A novel and flexible synthesis of pyranose spiroacetal derivatives, Tetrahedron Letters, vol. 39, no. 33, pp. 6061-6064.
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