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2013
Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E.M., Voges, M.J., Mock, E.D., Florea, B. I, van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F. , Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites, Journal of Medicinal Chemistry, vol. 56, no. 3, pp. 1262-1275. DOI
2012
Geurink, P.P., Prely, L.M., van der Marel, G.A., Bischoff, R., Overkleeft, H.S. , Photoaffinity labeling in activity-based protein profiling, Topics in current chemistry, vol. 324, pp. 85-113.
Li, J., Girard, G., Florea, B. I, Geurink, P.P., Li, N., van der Marel, G.A., Overhand, M., Overkleeft, H.S., van Wezel, G.P. , Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach, Organic & Biomolecular Chemistry, vol. 10, no. 43, pp. 8677-8683.
2011
Geurink, P.P., Prely, L.M., van der Marel, G.A., Bischoff, R., Overkleeft, H.S. , Photoaffinity Labeling in Activity-Based Protein Profiling, Reactivity Tuning in Oligosaccharide Assembly. DOI
Geurink, P.P., Florea, B. I, Overkleeft, H.S. , Activity-Based Profiling of 2-Oxoglutarate Oxygenases, Chemistry & Biology, vol. 18, no. 5, pp. 557-559. DOI
Geurink, P.P., Florea, B. I, Li, N., Witte, M.D., Verasdonck, J., Kuo, C.L., van der Marel, G.A., Overkleeft, H.S. , A levulinoyl ester based cleavable linker for activity-based protein profiling, Angewandte Chemie, International Edition, pp. in press.
2010
Geurink, P.P., Florea, B. I, Van der Marel, G.A., Kessler, B.M., Overkleeft, H.S. , Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates, Chemical Communications, vol. 46, pp. 9052-9054. DOI
Geurink, P.P., Liu, N., Spaans, M.P., Downey, S.L., van den Nieuwendijk, A., van der Marel, G.A., Kisselev, A.F., Florea, B. I, Overkleeft, H.S. , Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome's Chymotrypsin-like Sites, Journal of Medicinal Chemistry, vol. 53, no. 5, pp. 2319-2323. DOI
van der Linden, W.A., Geurink, P.P., Oskam, C., van der Marel, G.A., Florea, B. I, Overkleeft, H.S. , Proteasome selectivity towards Michael acceptor containing oligopeptide-based inhibitors, Org Biomol Chem, vol. 8, no. 8, pp. 1885-93. DOI
Geurink, P.P., Klein, T., Prely, L., Paal, K., Leeuwenburgh, M.A., van der Marel, G.A., Kauffman, H.F., Overkleeft, H.S., Bischoff, R. , Design of Peptide Hydroxamate-Based Photoreactive Activity-Based Probes of Zinc-Dependent Metalloproteases, European Journal of Organic Chemistry, no. 11, pp. 2100-2112. DOI
Florea, B. I, Verdoes, M., Li, N., van der Linden, W.A., Geurink, P.P., van den Elst, H., Hofmann, T., de Ru, A., van Veelen, P.A., Tanaka, K., Sasaki, K., Murata, S., den Dulk, H., Brouwer, J., Ossendorp, F.A., Kisselev, A.F., Overkleeft, H.S. , Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t, Chemistry & Biology, vol. 17, pp. 795-801.
Geurink, P.P., Florea, B. I, Li, N., Witte, M.D., Verasdonck, J., Kuo, C.L., van der Marel, G.A., Overkleeft, H.S. , A Cleavable Linker Based on the Levulinoyl Ester for Activity-Based Protein Profiling, Angewandte Chemie-International Edition, vol. 49, no. 38, pp. 6802-6805. DOI
2009
Klein, T., Geurink, P.P., Overkleeft, H.S., Kauffman, H.K., Bischoff, R. , Functional Proteomics on Zinc-Dependent Metalloproteinases using Inhibitor Probes, Chemmedchem, vol. 4, no. 2, pp. 164-170. DOI
Geurink, P., Klein, T., Leeuwenburgh, M., van der Marel, G., Kauffman, H., Bischoff, R., Overkleeft, H. , A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol, Org Biomol Chem, vol. 6, no. 7, pp. 1244-50. DOI
2008
Abello, N., Geurink, P.P., van der Toorn, M., van Oosterhout, A.J.M., Lugtenburg, J., van der Marel, G.A., Kerstjens, H.A.M., Postma, D.S., Overkleeft, H.S., Bischoff, R. , Poly(ethylene glycol)-Based Stable Isotope Labeling Reagents for the Quantitative Analysis of Low Molecular Weight Metabolites by LC-MS, Analytical Chemistry, vol. 80, no. 23, pp. 9171-9180. DOI
Geurink, P., Klein, T., Leeuwenburgh, M., van der Marel, G., Kauffman, H., Bischoff, R., Overkleeft, H. , A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol, Organic & Biomolecular Chemistry, vol. 6, no. 7, pp. 1244-1250. DOI
2006
Leeuwenburgh, M.A., Geurink, P.P., Klein, T., Kauffman, H.F., van der Marel, G.A., Bischoff, R., Overkleeft, H.S. , Solid-phase synthesis of succinylhydroxamate peptides: Functionalized matrix metalloproteinase inhibitors, Organic Letters, vol. 8, no. 8, pp. 1705-1708.