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Wilkins, O.M., Downey, S.L., Weyburne, E.S., Williams, D.A., Mirabella, A.C., Overkleeft, H.S., Kisselev, A.F. , Cell-line-specific high background in the Proteasome-Glo assay of proteasome trypsin-like activity, Analytical Biochemistry, vol. 451, pp. 1-3. DOI
Mirabella, A.C., Pletnev, A.A., Downey, S.L., Florea, B. I, Shabaneh, T.B., Britton, M., Verdoes, M., Filippov, D.V., Overkleeft, H.S., Kisselev, A.F. , Specific Cell-Permeable Inhibitor of Proteasome Trypsin-like Sites Selectively Sensitizes Myeloma Cells to Bortezomib and Carfilzomib, Chemistry & Biology, vol. 18, no. 5, pp. 608-618. DOI
Screen, M., Britton, M., Downey, S.L., Verdoes, M., Voges, M.J., Blom, A.E., Guerink, P.P., Risseeuw, M.D., Florea, B. I, van der Linden, W.A., Pletnev, A.A., Overkleeft, H.S., Kisselev, A.F. , The nature of pharmacophore influences active site specificity of proteasome inhibitors, J Biol Chem, vol. 285, pp. 40125-40134. DOI
Geurink, P.P., Liu, N., Spaans, M.P., Downey, S.L., van den Nieuwendijk, A., van der Marel, G.A., Kisselev, A.F., Florea, B. I, Overkleeft, H.S. , Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome's Chymotrypsin-like Sites, Journal of Medicinal Chemistry, vol. 53, no. 5, pp. 2319-2323. DOI
Britton, M., Lucas, M.M., Downey, S.L., Screen, M., Pletnev, A.A., Verdoes, M., Tokhunts, R.A., Amir, O., Goddard, A.L., Pelphrey, P.M., Wrigth, D.L., Overkleeft, H.S., Kisselev, A.F. , Selective Inhibitor of Proteasome's Caspase-like Sites Sensitizes Cells to Specific Inhibition of Chymotrypsin-like Sites , Chemistry & Biology, vol. 16, no. 12, pp. 1278-1289. DOI