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2006
El Oualid, F., Cohen, L.H., van der Marel, G.A., Overhand, M. , Inhibitors of protein: Geranylgeranyl transferases, Current Medicinal Chemistry, vol. 13, no. 20, pp. 2385-2427.
2005
El Oualid, F., van den Elst, H., Leroy, I.M., Pieterman, E., Cohen, L.H., Burm, B.E.A., Overkleeft, H.S., van der Marel, G.A., Overhand, M. , A combinatorial approach toward the generation of ambiphilic peptide-based inhibitors of protein : geranylgeranyl transferase-1, Journal of Combinatorial Chemistry, vol. 7, no. 5, pp. 703-713.
El Oualid, F., Baktawar, J., Leroy, I.M., van den Elst, H., Cohen, L.H., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Synthesis and biological evaluation of lipophilic Ca(1)a(2)L analogues as potential bisubstrate inhibitors of protein : geranylgeranyl transferase-1, Bioorganic & Medicinal Chemistry, vol. 13, no. 5, pp. 1463-1475.
2004
El Oualid, F., Burm, B.E.A., Leroy, I.M., Cohen, L.H., van Boom, J.H., van den Elst, H., Overkleeft, H.S., van der Marel, G.A., Overhand, M. , Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1, Journal of Medicinal Chemistry, vol. 47, no. 16, pp. 3920-3923.
2002
El Oualid, F., Bruining, L., Leroy, I.M., Cohen, L.H., van Boom, J.H., van der Marel, G.A., Overkleeft, H.S., Overhand, M. , Synthesis and biological evaluation of protein : Geranylgeranyltransferase I inhibitors based on the CaaX box: Incorporation of sugar amino acids as dipeptide isosters, Helvetica Chimica Acta, vol. 85, no. 10, pp. 3455-3472.
2000
Cohen, L.H., Pieterman, E., van Leeuwen, R.E.W., Overhand, M., Burm, B.E.A., van der Marel, G.A., van Boom, J.H. , Inhibitors of prenylation of Ras and other G-proteins and their application as therapeutics, Biochemical Pharmacology, vol. 60, no. 8, pp. 1061-1068.
1999
Overkleeft, H.S., Verhelst, S.H.L., Pieterman, E., Meeuwenoord, W.J., Overhand, M., Cohen, L.H., van der Marel, G.A., van Boom, J.H. , Design and synthesis of a protein : farnesyltransferase inhibitor based on sugar amino acids, Tetrahedron Letters, vol. 40, no. 21, pp. 4103-4106.
Cohen, L.H., Pieterman, E., van Leeuwen, R.E.W., Du, J.R., Negre-Aminou, P., Valentijn, A.R.P.M., Overhand, M., van der Marel, G.A., van Boom, J.H. , Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein : farnesyl transferase, Biochemical Pharmacology, vol. 57, no. 4, pp. 365-373.
1998
Overhand, M., Stuivenberg, H.R., Pieterman, E., Cohen, L.H., van Leeuwen, R.E.W., Valentijn, A.R.P.M., Overkleeft, H.S., van der Marel, G.A., van Boom, J.H. , Inhibitors of protein : farnesyl transferase and protein : geranylgeranyl transferase I: Synthesis of homologous diphosphonate analogs of isoprenylated pyrophosphate, Bioorganic Chemistry, vol. 26, no. 5, pp. 269-282.
1997
Overhand, M., Pieterman, E., Cohen, L.H., Valentijn, A.R.P.M., vanderMarel, G.A., vanBoom, J.H. , Synthesis of triphosphonate analogues of farnesyl pyrophosphate. Inhibitors of squalene synthase and protein:farnesyl transferase, Bioorganic & Medicinal Chemistry Letters, vol. 7, no. 18, pp. 2435-2440.
1995
Cohen, L.H., Valentijn, A., Roodenburg, L., Vanleeuwen, R.E.W., Huisman, R.H., Lutz, R.J., Vandermarel, G.A., Vanbooms, J.H. , Different Analogs of Farnesyl Pyrophosphate Inhibit Squalene Synthase and Protein-Farnesyltransferase to Different Extents, Biochemical Pharmacology, vol. 49, no. 6, pp. 839-845.
Valentijn, A.R.P.M., Dehaan, R., Hagens, S., Dekant, E., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , Synthesis of a Potential Enzyme-Specific Inhibitor of Squalene Synthase, Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands Chemical Society, vol. 114, no. 7, pp. 332-336.
Valentijn, A.R.P.M., Vandenberg, O., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , Synthesis of Pyrophosphonic Acid Analogs of Farnesyl Pyrophosphate, Tetrahedron, vol. 51, no. 7, pp. 2099-2108.
Valentijn, A.R.P.M., Broxterman, H.J.G., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , Synthesis of 1,6-Anhydro-2,3-Di-O-Farnesyl-5-O-([(Phosphonomethyl)Phosphinyl]Methyl)-Alpha-D-Galactofuranose - a Zaragozic Acid - Presqualene Pyrophosphate Hybrid, Journal of Carbohydrate Chemistry, vol. 14, no. 6, pp. 737-749.
1994
Valentijn, A.R.P.M., Vandenberg, O., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , A Novel-Approach Towards the Synthesis of Pyrophosphate Analogs of Farnesyl Pyrophosphate, Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands Chemical Society, vol. 113, no. 12, pp. 563-566.
1991
Valentijn, A.R.P.M., Vandermarel, G.A., Cohen, L.H., Vanboom, J.H. , An Expeditious Synthesis of Pyrophosphate Analogs of Farnesyl Pyrophosphate Using the Phosphorylating Agent Methyl Methylphosphonomorpholidate, Synlett, no. 9, pp. 663-664.