Publication Type:Journal Article
Source:Tetrahedron, Volume 59, Number 9, pp. 1589-1597 (2003)
Keywords:genome-linked peptides; uridylylated amino acid building blocks; solid phase peptide synthesis; rink amide resin; adenovirus-2 nucleoprotein; nucleopeptide fragment; poliovirus genome; nucleic-acids; rna-synthesis; protein; protection; strategy; gene
The uridylylated amino acid building blocks 2-cyanoethyl-(N-alpha-9-fluorenylmethoxy-carbonyl-tyrosin-4-yl)-(2',3'-di-O-acetyl-uridin-5'-yl) phosphate and 2-chlorophenyl-(N-alpha-fluorenyl-methoxycarbonyl-serin-3-yl)-(2',3'-di-O-acetyluridin-5'-yl) phosphate have been used successfully in an on-line SPPS of the VPgpU from the polio, coxsackie and cowpea mosaic virus. (C) 2003 Elsevier Science Ltd. All rights reserved.