Publication Type:Journal Article
Source:Tetrahedron Letters, Volume 38, Number 13, p.2249-2252 (1997)
Keywords:peptide nucleic-acids; DNA; pna; polyamide; backbone
An automated online solid-phase synthesis of Ac-cac ct T*GG TC t*ac ct-Gly-OH1 using standard DNA and appropriately protected PNA building blocks (2-5) is described. This chimera forms stable duplexes with complementary DNA and RNA. (C) 1997 Elsevier Science Ltd.