Stan van Boeckel | Bio-organic Synthesis

Universiteit Leiden

Stan van Boeckel, Ph.D.

Stan van Boeckel

Position:

Professor of Industrial Medicinal Chemistry

Expertise:

Drug discovery platform

Research theme:

Carbohydrates

E-mail address: boeckelcaavan@chem.leidenuniv.nl
Faculty/Unit: Faculty of Science, Leiden Institute of Chemistry, Bio-organic Synthesis
Office address: Gorlaeus Laboratories
Einsteinweg 55
2333 CC Leiden
roomnumber HB123

2005

Codee, J.D.C., Stubba, B., Schiattarella, M., Overkleeft, H.S., van Boeckel, C.A.A., van Boom, J.H., van der Marel, G.A. , A modular strategy toward the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy, Journal of the American Chemical Society, vol. 127, no. 11, pp. 3767-3773.

2004

Verhelst, S.H.L., Magnee, M.E., Wennekes, T., Wiedenhof, W., van der Marel, G.A., Overkleeft, H.S., van Boeckel, C.A.A., van Boom, J.H. , Glycosylation of cyclitols: Synthesis of neamine-type aminoglycosides, European Journal of Organic Chemistry, no. 11, pp. 2404-2410.

Verhelst, S.H.L., Wennekes, T., van der Marel, G.A., Overkleeft, H.S., van Boeckel, C.A.A., van Boom, J.H. , Synthesis of orthogonally protected 2-deoxystreptamine stereoisomers, Tetrahedron, vol. 60, no. 12, pp. 2813-2822.

Verhelst, S.H.L., Michiels, P.J.A., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Surface plasmon resonance evaluation of various aminoglycoside-RNA hairpin interactions reveals low degree of selectivity, Chembiochem, vol. 5, no. 7, pp. 937-942.

Codee, J.D.C., van den Bos, L.J., Litjens, R.E.J.N., Overkleeft, H.S., van Boeckel, C.A.A., van Boom, J.H., van der Marel, G.A. , Chemoselective glycosylations using sulfonium triflate activator systems, Tetrahedron, vol. 60, no. 5, pp. 1057-1064.

Filippov, D.V., van den Elst, H., Tromp, C.M., van der Marel, G.A., van Boeckel, C.A.A., Overkleeft, H.S., van Boom, J.H. , Parallel solid phase synthesis of tricomponent bisubstrate analogues as potential fucosyltransferase inhibitors, Synlett, no. 5, pp. 773-778.

2002

Verhelst, S.H.L., Wiedenhof, W., Ovaa, H., van der Marel, G.A., Overkleeft, H.S., van Boeckel, C.A.A., van Boom, J.H. , A stereoselective route towards highly functionalized 4,6-diaminocyclohexene derivatives, Tetrahedron Letters, vol. 43, no. 36, pp. 6451-6455.

Codee, J.D.C., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Probing the heparin - Antithrombin III interaction using synthetic pentasaccharides bearing positively charged groups, European Journal of Organic Chemistry, no. 23, pp. 3954-3965.

2001

van Hooft, P.A.V., Litjens, R.E.J.N., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Stereoselective transformations on D-glucose-derived eight-membered ring carbocycles, Organic Letters, vol. 3, no. 5, pp. 731-733.

van Hooft, P.A.V., van Swieten, P.F., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Montmorillonite K-10 clay assisted transformation of vinylketoses into spirochromans and arylketoses, Synlett, no. 2, pp. 269-271.

van Hooft, P.A.V., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Triisobutylaluminium mediated carbocyclisation of sugar derived spiroketals and ketosides, Tetrahedron Letters, vol. 42, no. 9, pp. 1769-1772.

1999

Buijsman, R.C., Basten, J.E.M., Dreef-Tromp, C.M., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains, Bioorganic & Medicinal Chemistry, vol. 7, no. 9, pp. 1881-1890.

Buijsman, R.C., Basten, J.E.M., van Dinther, T.G., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , Design and synthesis of a novel synthetic NAPAP-pentasaccharide conjugate displaying a dual antithrombotic action, Bioorganic & Medicinal Chemistry Letters, vol. 9, no. 14, pp. 2013-2018.

1998

van Hooft, P.A.V., Leeuwenburgh, M.A., Overkleeft, H.S., van der Marel, G.A., van Boeckel, C.A.A., van Boom, J.H. , A novel and flexible synthesis of pyranose spiroacetal derivatives, Tetrahedron Letters, vol. 39, no. 33, pp. 6061-6064.

01/09/2011

Bio-organic Synthesis